Nitric oxide (NO) plays a vital role in circulation, metabolism, and overall health. To safely increase NO levels, individuals should follow medical guidance through scientifically supported methods such as exercise and nutritional supplementation. Self-administered supplementation should be avoided to prevent adverse effects.

​1. Scientific Exercise​

Physical activity upregulates endothelial nitric oxide synthase (eNOS), enhancing NO production. Exercise also improves blood circulation, further supporting NO synthesis. Under medical supervision, structured exercise programs can effectively boost NO levels.

​2. Nutritional Supplementation​

Due to NO’s unstable molecular structure (rapidly degraded in the bloodstream), targeted nutrient intake may help sustain NO concentrations. Under professional guidance, the following supplements may support NO production:
​Amino acids​ (e.g., L-arginine, L-citrulline)
​Vitamin E​ (antioxidant protection)
​Folate​ (supports endothelial function)

​Additional Dietary Support​

A diet rich in fresh fruits (e.g., apples) and vegetables (e.g., celery) provides antioxidants that neutralize free radicals (e.g., superoxide), protecting NO from oxidative degradation and prolonging its bioavailability.